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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce548c4f4bb89fe768c6cee9790b8d1ea5f2f81b7b339c6ff7060e3680b076c5' 
  AND token = 'JSiL66IVTrRCXl2oZSOrrEUomJYrMY97EsHhC09HnLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}