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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1b0e8a7d4f5de8c75a687bb9403bbbbbaf84d7fdb9047c8af55e880a924d904' 
  AND token = 'rU780EQledOm0+Pfr+jP3WA6stB5869v306jGJGRarw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}