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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5aa9278424040bdd2e25c25f96cafc255d7f60a499d1d3aa9b21f23bd52d8c8' 
  AND token = 'gpaWlMEEOX7GO3oeA4A2SPUkAaBVhbjknz9kLTTgz9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}