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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f935dca50da979010c2e4dc541abbf82e2cb453723daf7bcb1b1d593322045b1' 
  AND token = '67Je/DI/KWkw5uxNc/i8K3etb6mU+IcV0TqLPhSA1ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}