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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7f7f66be0f7c364fb6ada6fe5df2f3c13234bbaaa9917c80bf328e95d89e2f8' 
  AND token = 'LOyj4IZc+1lYpUIN1eEqr1yVquZAHnvbBQsQRQNQtrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}