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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5783f66721c7a5a5b93011b8d5a19f0bff2e6813fff0d1de8e3f77d992fe5cd4' 
  AND token = 'zt5aPO6yJ0oDK9TYlTVLQfe0FEsKwcL1ZyRLf/1WqNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}