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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2876a49a1c35795c49926c226d7adc9c810571103b0232159faf7709a5b459d0' 
  AND token = 'ms0cN8DTUt01H0HaaWqZnWmKR9Rl7HxWlus425+w3Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}