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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06564729e587f2c44189e5fc3d42fe1dccd7186f12a800b7ea0de5ce9ae88e05' 
  AND token = 'koG1ZGReuv+X1ax56UOnG+jz5sD/Mq4NQGwjhRww2G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}