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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d69e1a09af535e21f4821ff5dcc330359db4197d65bf5efa2cd4e4d3dd32c36' 
  AND token = 'Ke8uIDMr0hZy+HOCh9wLZbKv3B9lyOi/P/cVyI91lcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}