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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac015f21c8d4501a5b0fe5aecd6a41a4b7853d66d2c956cd0df0d37e01df01b6' 
  AND token = 'QTahB3V1rQdOm7cpSpmGv/9HQ4wo58ihX9yOFrmKdK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}