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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90d84910bbe718a3679fe8a39eccf91b3373ce6d6e91a31a2cd92372d6ddb3a4' 
  AND token = 'NaFbvIHBY51AWaoTaQWfEsqTcY/MjqQAJ63kyWXDtPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}