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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a25b509d091e5f1097e022f2eefff09b323d74ac2a29adbacedfda1a6ef7d5' 
  AND token = '/NCOogVXHasZ32iDlKmVkAfGdx+Nf3bAPQfUs8HD8MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}