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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '848bde523e71fc71c99d1bbdbcff8f5306078320f3c3a10b2dcd7e25b6827f9a' 
  AND token = 'hkdweAhCv3FEaFPhCfkY9qnllEOV/6rRdqN9HCdx1Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}