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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '736bb1c011d23d8ae5b0c6eb90ad1031fd38e1b30612b3df1afaf17c03793114' 
  AND token = 'k9rUr0f7kD0XUibHCkMBji0CUT9FVPisoyj4ZGzfvAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}