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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58de52837005f8823641f74ce45c52bfb00d8940449b0656c2a03136de2653fe' 
  AND token = 'fs+HPEv2sY5DqIoAnWvTh2SFy4q4H3vQ1NOxDYvVTzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}