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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bbdd7ce10cd7c811361ff9aa34fa68c2aa73a3b7badfece41fea387fc600a502' 
  AND token = 'F53bHMdWKKJ8/7rIVnGj4jROA4+PoUpQopLzyjuexhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}