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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e98cbfa266bc92823ec2d1894c1cef19f2b8f547dab4a0103e2202e30a3232f4' 
  AND token = 'e+WymKueh1I0TSqHeNhe5MS5wKS46ZZ9PS4U5R9m3rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}