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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '228227383555bdb477895358d5f2669463e53666f7971e7562cb6d7f53d46e6f' 
  AND token = '38+5mE3h2GjE00RAzocSJHe/SZ+UIh58ehzjdjFmxfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}