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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1741ce3a2f1816902814c4dab26c11e394d98d2cda055d487e7d273fc11aeb52' 
  AND token = 'hkD9DFhkqOakjnJL1Klx/VoUQ4GVsLkaMZPf+t5qkXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}