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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d91b5bc1a6b12c748302fafb06e52cfc167b81a46a7ad8fed16266b1d46e575' 
  AND token = 'RaLkRjp/m0kwPRzZdV/nWmWEPF6q5c5bTkbuTAOXwuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}