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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e077b07b75d58976306edb97d8b64120172c6dcc41a6c71a06d03f3a40a90fa' 
  AND token = 'IcpRwMCQHkiXEFO32X/lXOa+r+HtOyX+oJUvYIqIeUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}