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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6fd29c39de2b45cb2bbc82249849d9843d22157e4e76e08f5b1551109933f2d' 
  AND token = '050ie2Z22S3x9HxAufL597Qv7hqBRoFEO3LuXoh0ijM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}