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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5195a6cd7262dcaf6f3632843e20ae1e5d44a1726d87a73d88afb102e2426703' 
  AND token = 'h4hBj73kmep2VDm0TPwE/V7YtUa6PTxyb7s1/yCr4Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}