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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8941a0f298b4e415f5ed2fc7401766e60d2f819ad208c4df03e36257a04904' 
  AND token = 'vVMzy6HpgLrNMs/0fbBqloX0+Ch2dOM45BNAAiDBtWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}