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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83651925e8a012036db372e60f5a3880fbbbe69e16ac06a3b920c4a55c33dc95' 
  AND token = 'DgK+0gopeQxVeadew8Yg0I7an+j35MesyfQmrGkWMBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}