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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38cf474c4fae362bc15b61b8ff96e1bf0c95828c3596d2091b2f7ca4296a15d4' 
  AND token = 'gSdkmwSvgtRk4ARlN0k/ouLURLS+a1PIPxcnkxld3pY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}