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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '352ae6f27acc899f473edb728900e41dfe2e74d8410d3d8554b19a51982458e7' 
  AND token = '41oFhyqzQxiRkjrPtR8jDD50APcaY4yiDekElWT+SWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}