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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f1161dc49338af1772878847813e8aedbb29a3568eac385dc915dffa657a305' 
  AND token = 'lqa+hPILlJSPK4bkgBDtmhyPm77b/FnRP6ROV3YbNgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}