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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c869e18d397e4bc9ccc55f2ea8b8199851374e1c4748633042d0043ae93cf9' 
  AND token = '2oh4wt4d3g/I3GmlmjbOgP8Qt5nr+V2ICrAUpWfsX5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}