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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e8d56ef2626dc8e9391ec8dc49d685ee6ac4f4152202fd2fcec4d0d47d5c4a' 
  AND token = 'cYxYo0Z795+8g0q+9IpzdbOPrhn0u+z0L/CvSdz+Awg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}