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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b25198f445320a2792bfa2ecdae6c649d3aefb45e4b2f7fe8d2f9023505ddb7' 
  AND token = 'z0PiQtVRKcLgIT7mZth5HmM+Rh4dSiUOn45xf+8Ub/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}