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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4041aedd7c7a9941e2d4667ae6a046cd1ea93091ff11bd635a462ee0ed12725' 
  AND token = 'UvAImfjwEw4xqi75h8I0cZyEWmNTeBBeF+efvsWwYjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}