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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0a01c1a4c5c17e14cbc696ff55661a86cd325a235f2857eef1b00e6ce5db49' 
  AND token = 'pY+l936QD/tDAY81fQPLByeWS+087rh2bZ7JSPWw950=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}