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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '072942934e91a638df496d11081a59f62d8bac0d7e41344870b0a354531d8777' 
  AND token = 'u5l0Kg3XK7qHWKio/foMmoz3RXtkxz6WdmigVScMhcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}