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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c123228faf98918133078ba3d50ec26b90757ea4844557f2c04794c425874288' 
  AND token = 'zyDRuvDFHB3tLMVGrEky8dBUABTu+TTWgAOaAc2h+CY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}