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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '041a3c17e55c77c616b1d537020dca07cc01be0f9edce6e3d8d4c612c4c37f7e' 
  AND token = '+vLiHEhK3qtxFqnR0aNjtIilVuUYOO8CZ9NjoiJsAOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}