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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a515caf89bcdc2f619d6026a03a18243fd8499d0e5eb2ea7f988f0a3214f35' 
  AND token = 'nfIw1apwosbl1ibpGsOsLYe5FTuRpjsbetDweN/pSmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}