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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0904369258fe1ae1f8f6d42d7d1ec572d06f8261993aa71dd49410ce7a1fd777' 
  AND token = 's7t6zBavchPb8NvRaHLZeTxtJD5gQ/3uO/NyjDkqPyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}