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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd7b071c4108b7495d5210f924cad5a24b37d69ef2a0ab900b164dc62b9fa7a1' 
  AND token = 'o9NmrS2Z2f4fFxfbxWDVBPI3y+fjHjYN33Brg0UHGlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}