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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5080e607ae25d2ce84cbebf42692e8ac7ced141c4717a56e3768bb1ae9f40c02' 
  AND token = 'sF/Jywekx9yaPqwy1gHMvg70c8O4eKX2U1xMS5L1SwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}