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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e81fedaeafadbaa8a82e2c04472b18542a6786764734f1ce5f0c3290c03cf0' 
  AND token = 'vYG45CNPJr0j3gWD9v08MfJ6IyoSVdaQtQdBQbfN07k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}