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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b220605a5e666be86b9330243c558bbc63ee6c2772f74e3c76385c3f919c02d5' 
  AND token = 'RJfT67LZUWAzXtsFE8z00sD8OvW3fWne0xstbAxfcjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}