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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '762d99cc09af8c4b341f4111946be1018d71523dc69252f91c431003454a1a30' 
  AND token = 'HheSrAfTeq2KDb0VjHXe1edDAA+fr9kxtMnkinwYMJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}