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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2133d93f6739214312979e816e6b17c12f4bf97a86ccef0aa46bf7e4c4adff8b' 
  AND token = 'OBMUhpH/cDXKfoYt686iGy+Qkpsq/3fhMnJtNfEUB0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}