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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '565c6ced75ce1cae0c11a915929db81acc6bc59eb58a9403d269e5fae70e1875' 
  AND token = 'u8kQm/jkxv1jhHyxKYIzBjv/iN4goyEXi+r12jXJMWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}