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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53269a92dd048395ef985a0b28e6169e35699667ba5247eb0aea1ae533b7a1b' 
  AND token = 'YqmAxs61v6MGENVyJ8XJCU+VrK5yRgaVcR0qwVCiv04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}