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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1dafa3829729ab78d858c4f371fa8093fe3fb87a1321defb16abf06ada156d2' 
  AND token = '1//fX4wQHZj2oKdEDfQe+JDvFZLl+j6SvUFpksboPBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}