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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c1860ace261fb1767f505e1f2e8ab60154969614cb5442f99cd96109d5baca5' 
  AND token = '9R5y1HWG5JDVPJypHAZ9EvTW8LDys9Ws3i/IM/F4EKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}