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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bff18fc8b201149c15f514cf272411876769a4af6d11a266598908ec4c829fd' 
  AND token = 'E+P8iCsOEYuys0vxf+ENS4kha03hmcXQ9JOoL/rtlcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}