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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71983735b3161ca30049ac86beb0aa802b12c3db3d9fde5ebdf0bb038d842cdc' 
  AND token = 'iwSsmaSK9HEuxStfxTnVnr4vpH68v7l0Nz5b7Q0zyGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}